2型糖尿病合并血管病变程度与hs-CRP、D-D与TC的相关性分析

目的探讨2型糖尿病并发症和hs-CRP、D-D与TC之间的联系,为糖尿病的早期防治提供实验依据。方法不同病程的糖尿病患者180例分成三组,每组60例,其中A组患者均患有合并大血管病变的糖尿病;B组患者合并微血管病变,并出现尿微量蛋白;C组患者均未出现并发症。另取无糖尿病患者60例(正常对照组,D组)。检测四组患者血液中hs-CRP、D-D、TC的浓度。结果与D组比较,A、B及C组hs-CRP、D-D及TC显著增加,差异有统计学意义(P<0.01);与C组比较,A及B组hs-CRP、D-D及TC显著增加,差异有统计学意义(P<0.01)。结论 hs-CRP、D-D、TC的浓度均是随着合并血管病变程度的增大而升高。

Objective Explore the relationship between NIDDM and hs-CRP,DD and TC,Provide the experimental basis for the early prevention of diabetes.Methods Patients with diabetes of different duration of 180 cases divided into three groups,60 cases of patients group.A patients were suffering from diabetes with macrovascular disease group B patients with microvascular disease and urinary micro protein group C were no complications.Another 60 cases of patients with diabetes（group D were the normal control group）.Detected hs-CRP,DD,the TC concentration in the four groups in the blood of patients.Results Compared with group D,A,B,and C of hs-of CRP,the DD and TC significantly increased there was significant difference（P〈0.01） ;Compared with group C,A and B groups of hs-CRP,and DD and TC significantly increased there was significant difference（P〈0.01）.Conclusion The hs-CRP,DD,TC concentration is elevated with vascular disease increases.