经皮射频消融术与根治性切除术在小肝癌治疗中的疗效研究

The curative effect of percutaneous RFA and radical resection to small hepatocellular carcinoma

目的探讨经皮射频消融术(RFA)治疗小肝癌的效果。方法将经影像学、病理学检查证实的小肝癌患者116例分为两组,分别行RFA和手术切除治疗,比较两组术后并发症的发生、术后1年两组肿瘤复发率及1、2、3年生存率。结果 RFA治疗组并发症发生率明显低于手术组,两组术后1年肿瘤复发率及1、2、3年生存率无统计学差异。结论对于小肝癌,肝功能不能耐受手术治疗或肿瘤实质位于靠近主要血管、胆管,切除困难的患者,RFA治疗具有与手术相同的效果,且并发症少。

Objective To discuss the curative effect of percutaneous radio frequency ablation （RFA） to small hepatocellular carcinoma. Methods 116 cases of patients with small hepatoccllular carcinoma, who were confirmed by imaging study and pathology, were divided into two groups, treated by RFA and surgical resection respectively. To compare the incidence of complication and the tumor recurrence rate a year after the operation, compare the survival rate 1 year, 2 years and 3 years respectively. Results For incidence of complication, the RFA treatment group was significantly lower than the operative group, and it had no significantly difference for the tumor recurrence ; in 1,2, 3 years, the suvival rate between the two groups had no significantly difference too. Conclusion Patients with small hepatocellular carcinoma and liver function, who cannot suffer operation or who＇ s tumor located close to the main blood vessels and bile duct so that not easy to resection, for them, RFA had less complications and same curative effect as the surgery.