中西药结合治疗溃疡性结肠炎的临床疗效和安全性研究

Clinical Analysis and Security for Integrative Medicine of Ulcerative Colitis

目的探讨临床上中西药结合治疗溃疡性结肠炎(UC)的临床疗效和安全性。方法选择我院90例溃疡性结肠炎患者,随机分为两组,对照组45例单用柳氮磺胺吡啶口服,治疗组45例给予中药组方和口服柳氯磺胺吡啶综合治疗。治疗后随访观察两组患者的临床不同疗效和不良反应发生情况。结果统计学比较结果显示,两组疗效对比治疗组总有效率为93.33%,对照组为77.78%,治疗组疗效明显优于对照组(P<0.05);而两组不良反应发生率无显著性差异(P>0.05)。结论中西医结合治疗溃疡性结肠炎临床疗效确切,不良反应少,安全性高,治疗优于单纯西药治疗,值得临床上推广和应用。

Objective Evaluate the clinical Integrative treatment and security of ulcerative colitis. Methods The 90 patients with ulcerative colitis in our hospital were randomly divided into two groups, 45 patients of control group were given oral sulfasalazine alone, and 45 cases of the treatment group received Chinese traditional medicine and sulfasalazine. Follow-up were given with different clinical efficacy and side effects was observed after treatment. Results The statistical comparison showed that The total effective rate was 93.33% in treatment group, 77.78% in control group, treatment group were significantly better than the control group （P〈0.05） ; adverse events of two groups was no significant difference （P〉0.05） . Conclusion Combination treatment of ulcerative colitis has better clinical curative effect, less toxicity, is better than western medicine treatment.