安徽省安庆地区婴幼儿腹泻轮状病毒的检测及流行病学特征

Epidemiological characteristics of infantile diarrhea caused by rotavirus in Anqing Anhui

目的了解安徽省安庆地区婴幼儿腹泻轮状病毒感染情况和流行病学特征。方法应用免疫层析双抗体夹心法对门诊和住院的2 467例婴幼儿腹泻患儿新鲜粪便标本进行A群轮状病毒检测,并进行流行病学分析。结果 2 467例标本中691例轮状病毒抗原检测阳性,总阳性率为28.0%。不同性别婴幼儿腹泻患儿轮状病毒感染率无明显差异。>6～12个月年龄段婴幼儿腹泻患儿轮状病毒感染率在所有年龄段中最高,与其他年龄段比较均有明显差异。轮状病毒感染率在12月份最高,8月份最低。在0～12个月年龄段中母乳喂养的婴儿轮状病毒感染率明显低于非母乳喂养者。结论 A群轮状病毒是安徽省安庆地区婴幼儿腹泻的重要病原菌,及时进行轮状病毒抗原检测,对于及时诊断和合理治疗具有重大意义。

Objective To understand the infection status and epidemiological characteristics of infantile diarrhea caused by rotavirus in Anqing Anhui.Methods Immune chromatography double antibodies sandwich method was performed to detecte A group of rotavirus in fresh dejection specimens of 2 467 cases of in-hospital or out-patient infants with diarrhea,and the epidemiological analysis was performed at the same time.Results In 2 467 cases of samples,691 cases（28.0%） were positive with rotavirus antigen.There was no obvious difference of positive rate of rotavirus antigen between different gender groups.The infection rate in infants of 6-12 months old was significantly higher than that in other age groups.Rotavirus infection rates reached to peak value and valley value in December and August respectively.In infants of 0-12 months old,the infection rate in infants receiving breast feeding was significantly lower than in infants not receiving breast feeding.Conclusion A group of rotavirus might be the most important pathogens causing infantile diarrhea in Anqing Anhui.Prompt detection of rotavirus antigen might be clinically significant for diagnosis and treatment.