期刊文献+

神经纤维瘤病I型累及眶部的MRI表现 被引量:5

Magnetic resonance imaging findings of orbital disease in neurofibromatosis type I patients
原文传递
导出
摘要 目的探讨神经纤维瘤病I型(NF1)累及眶部的MRI特征。方法回顾性分析2004年1月至2011年5月首都医科大学附属北京同仁医院80例符合国际医疗组织临床诊断标准的NF1型患者眼眶MRI表现,86侧眼眶受累。80例患者均行眼眶和(或)头颅MR成像,其中71例同时行增强扫描。结果79例85侧眶内从状神经纤维瘤,累及颞窝61侧,海绵窦61侧,翼腭窝51侧,颞下窝31侧,增强后71侧轻度一中等强化;蝶骨大翼发育不良所致眶壁骨质缺损79侧,蝶骨小翼发育不良72侧;眼球增大32侧,视神经胶质瘤5侧;伴发脑实质多发T2WI高信号灶53例。结论NF1容易累及眼眶,MRI可直接显示眶部受累范围以及伴发的其他异常。 Objective To explore the magnetic resonance imaging (MRI) features of neurofibromatosis type 1 (NF1) with orbital involvement. Methods We retrospectively reviewed the MRI findings of orbital abnormalities in 80 NF1 patients (86 orbits). The diagnosis was confirmed by the updated National Institute of Health ( NIH ) criteria. All of them underwent MRI scans of orbit or brain while 71 patients had contrast enhancement. Results The orbital abnormalities were documented in 80 patients. And 79 cases (85 orbits) had plexiform neurofibroma in orbit and/or adjacent regions. The orbital involvements extended to superficial temporal fossa ( n = 61 ) , infratemporal fossa ( n = 31 ) , cavernous sinus ( n = 61 ) and pterygopalatine fossa (n = 51 ). There was mild-to-moderate enhancement in 71 orbits on contrastenhanced MRI examinations. There were localized defects of orbital walls because of sphenoid bone dysplasia of greater wing (n =79), sphenoid bone dysplasia of lesser wing (n = 72), augmentation (glaucoma) of eyeballs (n = 32) and optic nerve gliomas (n = 5 ). And 53 cases had hyperintense lesions on T2-weighted brain images. Conclusion Orbital involvement is common for NF1. And MRI is a useful tool of evaluating the extent of involvements and other abnormalities in the NF1 patients.
出处 《中华医学杂志》 CAS CSCD 北大核心 2012年第29期2042-2045,共4页 National Medical Journal of China
关键词 神经纤维瘤病1型 眼眶 神经纤维瘤 丛状 Neurofibromatosis 1 Orbit Neurofibroma, plexiform
  • 引文网络
  • 相关文献

参考文献19

  • 1North K. Neurofibromatosis Type 1 in Childhood. London: MacKeith Press, 1997:31-33.
  • 2Gutmann DH, Aylsworth A, Carey JC, et al. The diagnostic evaluation and multidisciplinary management of neurofibromatosis 1 and neurofibromatosis 2. JAMA, 1997, 278:51-57.
  • 3Drappier JC, Khosrotehrani K, Zeller J, et al. Medical management of neurofibromatosis 1 : a cross-sectional study of 383 patients. J Am Acad Dermatol, 2003, 49:440-444.
  • 4Friedman JM. Neurofibromatosis 1: clinical manifestations and diagnostic criteria. J Child Neurol, 2002, 17:548-554.
  • 5Lin V, Daniel S, Forte V. Is a plexiform neurofibroma pathognomonic of neurofibromatosis type I ? Laryngoscope, 2004, 114:1410-1414.
  • 6Bongiorno MR, Pistone G, Aricb M. Manifestations of the tongue in Neurofibromatosis type 1. Oral Dis,2006,12 : 125-129.
  • 7Korf BR. Plexiform neurofibromas. Am J Med Genet, 1999, 89: 31-37.
  • 8Cunha KS, Barboza EP, Dias EP, et al. Neurofibromatosis type I with periodontal manifestation. A case report and literature review. Br Dent J. 2004. 196:457-460.
  • 9Lira R, Jaramillo D, Poussaint TY, et al. Superficial neurofibroma: a lesion with unique MRI characteristics in patients with neurofibromatosis type 1. AJR Am J Roentgenol,2005, 184: 962 -968.
  • 10Mautner VF, Hartmann M, Kluwe L, et al. MRI growth patterns of plexiform neurofibromas in patients with neurofibromatosis type 1. Neuroradiology, 2006, 48:160-165.

二级参考文献11

  • 1范先群,周慧芳,陶凯,陈晓军.复合性眼眶骨折修复重建术中计算机辅助设计和辅助制造技术的应用[J].中华眼科杂志,2005,41(12):1092-1097. 被引量:24
  • 2Kwiat DM, Bersani TA, Hodge C, et al. Surgical technique : twostep orbital reconstruction in neuroflbromatosis type 1 with a matched implant and exenteration. Plast Reconstr Surg, 2004,20: 158-161.
  • 3Reed D, Robegson WD, Rootrnan J, et al. Plexiform neurofibromatosis of the orbit: CT evaluation. Am J Neuroradiol, 1986,7:259-263.
  • 4Harkens K, Dolan KD. CorreLative imaging of sphenoid dysplasia accompanying neurofibromatosis. Ann Otol Rhinol Laryngol, 1990, 99:137-141.
  • 5Neurofibromatosis. Conference statement. National Institutes of Health Consensus Development Conference. Arch Neurol, 1988, 45:575-578.
  • 6Jackson IT, Laws ER Jr, Martin RD. The surgical management of orbital neuroflbromatosis. Plast Reconstr Surg, 1983, 71: 751-758.
  • 7Krastinova-Lolov D, Harnza F. The surgical management of cranioorbital neurofibromatosis. Ann Plast Surg, 1996,36:263-269.
  • 8Jacquemin C, Bosley TM, Svedberg H. Orbit deformities in craniofacial neurofibromatosis type I. Am J Neuroradiol, 2003, 24 : 1678-1682.
  • 9Poole MD. Experiences in the surgical treatment of cranio-orbital neurofibromatosis. Br J Plast Surg, 1989,42 : 155-162.
  • 10Hunt JA, Hobar PC. Common craniofacial anomalies : conditions of craniofacial atrophy/hypoplasia and neoplasia. Plast Reconstr Surg, 2003,111:1497-1510.

共引文献1

同被引文献39

引证文献5

二级引证文献4

;
使用帮助 返回顶部