莫西沙星联合氨溴索治疗慢性支气管炎急性发作疗效观察

Effect of moxifloxacin combined with ambroxol in the treatment of acute exacerbation of chronic bronchitis

目的观察莫西沙星联合氨溴索雾化吸入治疗慢性支气管炎急性发作的临床效果。方法将84例慢性支气管炎急性发作的患者随机分两组,对照组和治疗组各42例。对照组给予沙丁胺醇联合左氧氟沙星治疗,治疗组给予氨溴索联合莫西沙星治疗,观察对比两组的治疗效果。结果治疗组总有效率95.24%,对照组组总有效率85.71%,差异有统计学意义(P<0.05)。治疗组咳痰消失时间(5.05±1.66)d、喘息消失时间(3.71±0.83)d、治疗天数(6.75±1.13)d,与对照组比较明显缩短(P<0.05)。结论氨溴索雾化吸入联合莫西沙星治疗慢性支气管炎急性发作疗效好,值得临床推广。

Objective To investigate the effect of moxifloxacin combined with ambroxol in the treatment of acute exacerbation of chronic bronchitis.Methods 84 cases of acute exacerbation of chronic bronchitis were randomly divided into two groups,control group and treatment group with 42 cases each.Control group received salbutamol and levofloxacin,treatment group implied with ambroxol and moxifloxacin,the therapeutic effect of two groups were analyzed.Results Compared with the control group,treatment group performed better in the aspects of lencocyte count,neutrophil percentage,the total amelioration efficiency（P〈0.05）.Conclusion The therapeutic effect of moxifloxacin combined with ambroxol in the treatment of acute exacerbation of chronic bronchitis is good and worthy of promotion.