钯/碳高效绿色催化Suzuki交叉偶联反应

Pd/C-Catalyzed Highly Efficient and Green Suzuki Cross-Coupling Reaction

开发了一个以钯/碳为催化剂高效绿色催化Suzuki反应制备联苯类化合物的新方法.该体系以环境友好的聚乙二醇400的水溶液为反应溶剂,加入离子液体1-甲基-3-丁基咪唑双三氟甲磺酰亚胺盐,可高效催化溴代芳烃与芳基硼酸的Suzuki交叉偶联反应,并且催化剂可以循环利用4次而催化效率没有明显降低.

An efficient protocol for the Suzuki reaction catalyzed by Pd/C has been developed in a green sovent. This method is able to prepare a variety of biaryls in high yields. In the presence of 1-butyl-3-methylimidazolium bis[（trifluoro- methyl）sulfonyl]imide, the cross-coupling reaction of aryl bromides with arylboronic acids proceed smoothly in PEG400 aqueous at 45 ℃. The catalyst could be recycled four times without loss of activity.