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急性有机磷农药中毒恢复期患者诱发电位的变化及意义

The changes and its significance of evoked potential in recovery period of patients with acute organic phosphorus pesticide poisoning
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摘要 目的探讨急性有机磷农药中毒恢复期患者诱发电位的变化及意义。方法按中毒程度,将急性有机磷农药中毒恢复期患者分为A组(轻度中毒者)、B组(中度中毒者)和C组(重度中毒者)。对各组进行短潜伏时体感诱发电位(SSEP)和脑干听觉诱发电位的测定(BAEP),并同对照组进行比较。结果 SSEP的测定结果表明,与对照组比较,A组的P15波以及B组、C组的各波潜伏时均明显延长(P<0.05,P<0.01)。BAEP的测定结果表明,与对照组比较,BAEP各波潜伏时除A组的Ⅰ波外,各组各波潜伏时均显著延长(P<0.05,P<0.01),峰间潜伏时除A组的Ⅰ-Ⅲ波外,各组各峰间潜伏时均显著延长(P<0.05,P<0.01)。结论处在恢复期的急性有机磷中毒患者的诱发电位仍有异常,这种异常可作为急性有机磷农药中毒所致中枢神经功能损伤的评价指标之一。 Objective To study the changes and its significance of evoked potential in recovery period of patients with acute organic phosphorus pesticide poisoning.Methods According to the degree of poisoning,the patients with acute organic phosphorus pesticide poisoning were divided into group A(mild poisoning),group B(moderate poisoning) and group C(severe poisoning).Each group was measured with the short-latency somatosensory evoked potentials(SSEP) and brainstem auditory evoked potentials(BAEP) compared with the control group.Results Compared with the control group,the latencies of P15 wave in A group and all the waves in B group and C group were significantly prolonged(P〈0.05,P〈0.01) in SSEP.The results of BAEP showed that,compared with the control group,the latencies and interpeak latencies of each group were significantly delayed except for Ⅰwave and I-III interpeak latency in group A(P〈0.05,P〈0.01).Conclusion The evoked potentials were abnormal in patients with acute organic phosphorus poisoning in recovery period,which could be used as an evaluating index in the central nerve function damage caused by acute organic phosphorus pesticide poisoning.
出处 《济宁医学院学报》 2012年第4期256-258,共3页 Journal of Jining Medical University
关键词 急性有机磷农药中毒 恢复期 临床诱发电位 Acute organic phosphorus pesticide poisoning Recovery period Clinical evoked potentials
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