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IMP3在人类肿瘤细胞中的表达及研究现状 被引量：3

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摘要 胰岛素样生长因子ⅡmRNA结合蛋白3(IMP3)是胰岛素样生长因子RNA结合蛋白家族中的一种,它在胚胎形成时调节胰岛素样生长因子Ⅱ(IGF-Ⅱ)的转录,主要在胚胎时期和肿瘤组织中表达,现将IMP3在人类肿瘤细胞中的表达以及研究现状作一综述。
作者 张冉 敖启林
机构地区 济宁医学院附属医院 华中科技大学同济医学院
出处 《济宁医学院学报》 2012年第4期297-301,共5页 Journal of Jining Medical University
关键词 胰岛素样生长因子ⅡmRNA结合蛋白3 肿瘤 标志物
分类号 R73 [医药卫生—肿瘤]
  • 相关文献

参考文献10

  • 1Ikenberg K, Fritzsche FR, Zuerrer-Haerdi U, et al. Insulin-like growth factor H RNAbinding protein 3(IMP3)is overexpressed in prostate cancer and orrelates with higher Gleason scores[J]. BMC Cancer,2010,10:341.
  • 2苏鹏,杨其峰,周志强,王妍,刘文君,张庆慧.乳腺癌中IMP3表达及其与临床病理特征的关系[J].临床与实验病理学杂志,2010,26(1):18-21. 被引量：7
  • 3李康华,黄跃平,张俊,李国军,李思鸿.IMP3蛋白在骨肉瘤组织中的表达与临床意义[J].细胞与分子免疫学杂志,2009,25(5):426-427. 被引量：7
  • 4Slosar M,Vohra P,Prasad M, et al. Insulin-like growth factor mRNA binding protein 3(IMP3)is differentially expressed in benign and malignant follicular patterned thyroid tumors[J]. Endocr Pathol, 2009,20 (3) : 149-157.
  • 5陈照丽,邢学忠,李宝重,石素胜,冯晓莉,周芳,谭晓刚,赫捷.IMP3在食管鳞癌中高表达是独立预后因素[J].中国现代医学杂志,2010,20(23):3583-3587. 被引量：3
  • 6Prince SN, Foulstone EJ, Zaccheo OJ, et al. Functional evalu ation of novel soluble insulin-like growth factor(IGF)-Ⅱ- specilie ligand traps based on modified domain 11 of the human IGF2 receptor[J]. Mol Cancer Ther, 2007,6 (2): 607- 617.
  • 7王瑞权,黄志芳,陈志梅,薛洪燕.HIF-1a及IMP3在胃癌中的表达及意义[J].现代实用医学,2011,23(10):1183-1185. 被引量：10
  • 8Marcoliver R, Florian R, Fritzs C, et al. IMP3 expression in lesions of the biliary tract:a marker for high-grade dysplasia and an independentprognostic faetorin bile duct carcinomas [J]. Human Pathology,2009,40(10): 1377-1383.
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  • 10Findeis-Hosey JJ, Yang Q, Spaulding BO, et al. IMP3 expression iscorrelated with histologic grade of lung adenocarcinoma [J]. Hum Pathol,2010,41(4) :477-484.

二级参考文献44

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  • 7Liao B,Hu Y,Herrick D J,et al.The RNA-binding protein IMP-3 is a translational activator of insulin-like growth factor Ⅱ leader-3 mRNA during proliferation of human K562 leukemia cells[J].J Biol Chem,2005,280(18):18517-24.
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共引文献19

同被引文献35

  • 1康春生,浦佩玉,李捷,于士柱,王虎,江荣才,董伦,王广秀.人脑胶质瘤表皮生长因子受体表达及与增殖和侵袭相关性的研究[J].中国神经精神疾病杂志,2004,30(5):349-352. 被引量：7
  • 2万德森.低位直肠类癌的外科治疗[J].中国实用外科杂志,2005,25(3):143-144. 被引量：29
  • 3黄文斌（摘译.IMP3是宫颈原位腺癌一个新的标记物[J].临床与实验病理学杂志,2007,23(4):411-411. 被引量：25
  • 4Wang T, Hokins D, Schmidt C, et al. Identification of genes differentially over expressed in lung squamous cell carcinoma using combination of cDNA subtraction and microarray alysis [J]. Oneogene, 2000,19(12) : 1519-1528.
  • 5Yuan R H,Wang C C,Chou C C,et al. Diffuse expression of RNA-binding protein IMP3 predicts high-stage lymph node metastasis and poor prognosis in colorectal adenocarcinoma [J]. Ann Surg Oneol,2009,16(6):1711-1719.
  • 6Yantiss R K,Woda B A,Fanger G R,et al. KOC(K homology domain containing protein over expressed in cancer) : a novel molecular marker that distinguishes between benign and ma lignant lesions of the pancreas[J]. AmJ Surg Pathol, 2005,29 (2) : 188-195.
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  • 8Su Q, Liu Y F, Zhang J F, et al. Expression of insulin-like growth factor in hepatitis,cirrhosis and hePatocellular carol noma:its relationship with hepatitis P2 virus antigen expres sion[J]. HeDatology,1994,20(4):788-799.
  • 9Sohda T,Oka Y,Iwata k,et al. Co-localisation of insulin-like growth factor Ⅱ and the proliferalion marker MIBJ in hepa tocellular carcinomacells[J]. J Clin Pathol, 1997,50(2) : 135- 137.
  • 10Findeis-Hosey J J,Yang Q,Spulding B O,et al. IMP3 expres sion iscorrelated with histologic grade of lung adenocarcinoma [J]. Hum Pathol,2010,41(4) :477-484.

引证文献3

二级引证文献13

济宁医学院学报
2012年 第4期

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