NT-BNP在心源性哮喘与肺源性哮喘鉴别诊断中的临床意义

The diagnostic value of brain natriuretic peptide in patients with cardiac asthma or pulmonary asthma

目的:研究B型利钠肽(NT-BNP)在心源性哮喘与肺源性哮喘鉴别诊断中的临床意义。方法:选择以呼吸困难为主要症状的300例患者,其中,心源性呼吸困难(甲组)和肺源性呼吸困难(乙组)各150例,体检健康者150例为对照组,测定其血浆NT-BNP浓度,分析各组之间血浆NT-BNP浓度的差异。结果:甲组血浆NT-BNP浓度显著高于乙组,具有统计学意义(P<0.01)。结论:血浆NT-BNP有助于快速准确鉴别心源性哮喘和肺源性哮喘。

Objective ：To evaluate the diagnostic value of brain natriuretic peptide（BNP） in patients with cardiac asthma or pulmonary asthma. Methods： Blood samples of 150 cardiac asthma, 150 pulmonary asthma, 150 healthy individuals as control group were collected. Samples of serum BNP concentration were analyzed, followed by comparisons of BNP levels among all groups. Results：The BNP level in cardiac asthma patients was significantly higher than that of pulmonary asthma patients and normal control group（ P 〉 0. 01 ）. There was no significant difference of BNP level between pulmonary asthma patients and normal group （ P 〉 0.05 ）. The plasma BNP level in cardiac asthma group was higher than that in pulmonary asthma group （ P 〈 0. 05 ）. Conclusion ： Measurement of plasma BNP is a rapid diagnostic method for cardiac asthma and pulmonary asthma.