轮状病毒性肠炎患儿生化指标检测结果分析

Biochemical indicator of rotaviral enteritisinfants

目的:回顾性分析小儿轮状病毒性(RV)腹泻与血清生化指标的检测结果。方法:检测230例RV阳性肠炎患儿(观察组)及60例RV阴性肠炎患儿(对照组)血清肝功能及心肌酶活性,综合分析其实验结果。结果:观察组转氨酶心肌酶谱各指标均明显高于对照组,差异有显著性(P<0.05),尤以CK、CK-MB最为显著;有脱水酸中毒组ALT、AST、LDH、HBDH、CK、CK-MB明显高于无脱水酸中毒组,差异有显著性(P<0.05);治疗后转氨酶及心肌酶活性各指标均明显改善。结论:RV腹泻可引起血清心肌酶谱和转氨酶异常,导致肠道外脏器损伤,早期监测血清转氨酶和心肌酶的变化有利于临床及早预防并采用相应的措施。

Objective. To explore the correlation between rotavirak virus （RV）infection and ex- traintestine injury. Methods： Serum hepatic function and myocardium enzyme activity of 230 RV positive enteritis infants （Observation group） and 230 RV negative enteritis infants （control group） were measured and compared. Results： Aminotransferase and myocardium enzyme activity related indexes were significanlt higher in observation group （P^0.05）, especially CK and CK- MB. Patients with dehydration and acido- sis had significantly higher level of ALT, AST, LDH, HBDH, CK and CK- MB than these without dehy- dration or acidosis （P%0.05）. Aminotransferase and myocardium enzyme activity were significantly im- proved after treatment. Conclusions： RV diarrhea can cause abnormal aminotransferase and myocardium enzyme activity, and extraintestinal injury. Early monitoring of serum aminotransferase and myocardium is valuable in prevention and treatment.