运动干预对肥胖青少年体成分、血脂、胰岛素抵抗及超敏C反应蛋白的影响

The Effect of Exercise Intervention on Body Composition,Blood Lipid,Insulin Resistance and High-Sensitivity C-Reactive Protein in Obese Adolescents

目的:观察4周小强度长时间有氧运动对肥胖青少年体成分、血脂、胰岛素抵抗和超敏C反应蛋白(hs-CRP)的影响,探讨CRP和体脂率、血脂和胰岛素等心血管疾病危险因素的关系。方法:对肥胖青少年进行运动干预,测试干预前后身体形态、空腹血糖、血脂和血胰岛素、血清hs-CRP等指标。结果:运动干预前,hs-CRP与BMI、体脂百分比、腰围等呈显著正相关,与HDL-C呈显著负相关;运动干预后,体重、BMI、体脂百分比、腰围、臀围等均显著下降,血脂(TC、TG、LDL-C)、hs-CRP水平和胰岛素抵抗指数显著降低。结论:肥胖青少年血清hs-CRP水平升高,腰围、血脂代谢紊乱和胰岛素抵抗等因素与hs-CRP水平存在显著相关,可能是肥胖患者发生心血管等病理变化的综合危险因素;4周有氧运动能有效降低肥胖青少年的腰围值、体脂率和hs-CRP水平,改善脂代谢和胰岛素抵抗,对预防和延缓肥胖青少年心血管疾病的发生和发展将产生积极的作用。

Purpose： to examine the effect of 4-week aerobic exercise with low intensity on body composition, blood lipid, insulin resistance and high-sensitivity C-reactive protein （hs-CRP） in obese adolescents and the correlation between CRP and cardiovascular risks. Methods： Exercise intervention has been exerted on obese adolescent to test the changes before and after in body morphology, fasting blood sugar, blood lipid, insulin, serum hs-CRP, etc. Results： Before intervention, there is a significantly positive correlation between hs-CRP and BMI, fat percentage, waist circumferences, etc. , and a significantly negative correlation with HDL-C. After intervention, there are significant reduction of body weight, BMI, fat percentage, waist and hip circumferences as well as blood lipid （TC, TG, LDL-C）, hs-CRP and insulin resistance index. Conclusion： The significant correlation may be the factors to lead to cardiovascular disorders. 4-week aerobic exercise with low intensity can effectively reduce body weight, fat percentage, and hs-CRP of subjects, improve their lipid metabolism, insulin resistance, which prevents and decreases the risk of future cardiovascular events.