针灸治疗排卵障碍性不孕症临床疗效的Meta分析

目的用Meta分析的方法探讨针灸对排卵障碍性不孕的治疗作用。方法双人独立全面检索1983～2011年间公开发表在国内外杂志的有关针灸治疗排卵障碍性不孕症的相关文献,以RR值作为效应指标计算针灸相对于克罗米芬对排卵障碍性不孕症的治疗优势。Stata11.0软件进行异质性检验,并根据异质性检验结果采用固定或随机效应模型合并RR值,P值及95%CI。结果与单纯服用格罗米芬组相比针灸组的受孕成功率是其1.47倍[95%CI(1.27～1.71)],中药配合针灸治疗组其受孕成功率是其2.02倍[95%CI(1.42～2.87)]。结论针灸是治疗排卵障碍性不孕症的有效方法,针灸配合中药治疗排卵障碍性不孕的效果明显,值得推广。

Objective To evaluate the clinical effects of acupuncture on ovulatory obstacle infertility using meta-analysis method. Methods Literatures from 1983 up to 2011 which involved in exploring the relationship between acupuncture on ovulatory obstacle infertility were widely searched by two individuals and RR as an quantitative effect indicator was used for comparing the effect of acupuncture and clomiphene （CC） on ovulatory obstacle infertility. Statal 1.0 was used for heterogeneity test and according to the results we determine if a fixed or a random effect model was used for getting the pooled RR, P value and the 95% confidence interval of RR. Results The successful pregnant rate of acupunctta＇e group is 1.47 fold of CC only group 95%CI（1.27-1.71）. If traditional Chinese medicine added to the acupuncture group the successful pregnant rate is 2.02 fold to CC only group 95%CI （1.42-2.87）. Conclusion Acupuncture is an effective method for treating with ovulatory obstacle infertility and acupuncture added with traditional Chinese medicine is better.