亚胺氧自由基与酚类的反应

The Reaction of Iminoxy Radical with Phenols

研究了亚胺氧自由基 (iminoxyradical)与酚类的反应 ,一步合成了取代苯并唑、萘并及喹啉并唑类衍生物 ,同时探讨了反应机理 .

p-Chlorobenzaldoxime dehydrodimer, which decomposed to iminoxy radicals on heating, reacts with substituted phenols giving acetylamino, t-butyl, dimethyl, methoxy and phenyl substituted 2-(4-chlorophenyl)benzoxazole derivatives. From 1- or 2-naphthol, 8-hydroxyquinoline and bisphenol A, 2-(4-chlorophenyl)naphth[2,1-d]oxazole(6), 2-(4-chlorophenyl)naphth[1,2-d]oxazole(5), 2-(4-chlorophenyl)oxazolo[4, 5-h]quinoline(7) and 2, 2-bis[5-(2-(4'-chlorophenyl)benzoxazolyl)]-propane(8) were obtained. This is a new kind of radical substitution reaction. And a mechanism of the reaction is proposed.