原发性肝癌患者检测血清VEGF的临床意义

CLINICAL SIGNIFICANCE OF DETECTING SERUM VEGF OF PRIMARY LIVER CANCER PATIENTS

目的:探讨血清血管内皮生长因子(VEGF)对原发性肝癌的诊疗价值。方法:采用ELISA法检测40例原发性肝癌患者、30例健康成年人和30例其他恶性肿瘤患者血清VEGF水平。结果:原发性肝癌患者血清VEGF水平明显高于健康成年人和其他恶性肿瘤患者(P<0.01);且原发性肝癌VEGF与AFP呈正相关(P<0.05)。结论:血清VEGF可能成为原发性肝癌的一个新的肿瘤标志物,用于原发性肝癌的诊断。

Objective： To investigate the diagnosis and treatment value of detecting vascular endothelial growth factor （VEGF） level in serum of primary liver cancer patients.Methods：ELISA was used to detect the VEGF level in serum of 40 primary liver cancer patients, 30 healthy adults and 30 other malignant tumor patients. Results：The VEGF level in serum of primary liver cancer patients was obviously higher than that of healthy adults and other malignant tumor patients （P（0.01）. Moreover, the AFP had positive correlation with VEGF in primary liver cancer （P~ 0.05）.Conclusions：Serum VEGF level may be a new tumor marker for primary liver cancer, and canbe used in diagnosis of primary liver cancer.