超低频经颅磁刺激对痉挛型脑瘫患儿运动功能的影响

Effect of infra-low-frequency transcranial magnetic stimulation on motor function in children with spastic cerebral palsy

目的探讨超低频经颅磁刺激(TMS)对痉挛型脑瘫患儿的治疗效果。方法将75例痉挛型脑瘫患儿随机分为对照组(33例)和治疗组(42例),对照组只接受常规的综合康复训练进行治疗,治疗组则在综合康复训练的同时,进行超低频TMS治疗。应用粗大运动功能测试量表(GMFM)和精细运动功能测试量表(FMFM)对两组患儿进行评价,比较两组患儿治疗1个月和3个月后运动功能的变化。结果治疗1个月后,治疗组患儿坐位能区的改善优于对照组(P<0.05)。治疗3个月后,治疗组患儿坐位能区、爬与跪能区及GMFM总分的改善均优于对照组(P<0.05);上肢关节活动能力、抓握能力、操作能力的改善亦均优于对照组(P<0.05)。结论超低频TMS可以有效改善痉挛型脑瘫患儿的运动功能。

Objective To study the therapeutic effects of infra-low-frequency transcranial magnetic stimulation in children with spastic cerebral palsy. Methods Seventy-five children with spastic cerebral palsy were randomly divided into two groups： control （n = 33 ） and treatment groups （n = 42 ）. The treatment group accepted infra-low-frequency transcranial magnetic stimulation besides conventional comprehensive rehabilitation therapy. The control group only accepted conventional comprehensive rehabilitation therapy. Motor functions were assessed by gross motor function measure （GMFM） and fine motor function measure （FMFM） at one and three months after treatment. Results Improvement in the ability to sit in the treatment was better than in the control group at one month after treatment （P 〈 0.05）. Improvement in the ability to sit, crawl and kneel, total score of GMFM, and improvement of joint active ability of limbs, grasping ability the ability to sit, crawl and kneel, total score of GMFM, and improvement of joint active ability of limbs, grasping ability and operating ability in the treatment group were better than the control group at three months after treatment （P 〈 0.05）.Conclusions Infra-low-frequency transcranial magnetic stimulation can effectively improve motor function in children with spastic cerebral palsy.