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四环素骨诱导活性材料整复牙槽缺损的实验研究 被引量:4

Experimental study on repairing the defect in alveolar bone with tetracycline activated materials for bone guide.
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摘要 目的 :将盐酸四环素处理的人离体非功能牙块用于诱导骨再生技术中 ,观察和比较其对牙槽骨再生修复的影响。方法 :拔除大鼠第一磨牙近中根做人工牙槽缺损。置入盐酸四环素处理的离体人牙块 ,以盐酸处理的离体人牙块为阳性对照 ,未做任何处理的离体人牙块为阴性对照。不同时期取材做组织观察和评价。结果 :四环素处理组炎症反应小 ,早期成骨明显。中晚期成骨量明显高于对照组。结论 :盐酸四环素处理的人离体非功能牙块有抑制骨吸收 ,诱导、促进牙槽骨再生等作用。 Objective:The effect on alveolar bone regeneration and repair was observed and compared with guide bone regeneration technique -isolated human dentin blocks treated with tetracycline-HCL.Methods:The first molar mesial roots of rats were extracted as defects in alveolar bone and the isolated human dentin blocks treated with tetracycline-HCL as positive control and and untreated with anything as negative control were implanted the defect sites for histologic observation and evaluation at the different periods.Results:There is less inflammatory (in tetracycline treatment groups than control at early stages and they showed marked osteaogenesis),but the osteogenic quantity is larger than control groups at middle and late stages. Conclusion:The isolated teeth blocks treated with tetracycline HCL have actions on inhibiting bone resorption, and promoting alveolar bone generation.
作者 刘牧菲
出处 《口腔医学纵横》 CSCD 2000年第3期190-192,共3页 Journal of Comprehensive Stomatology
基金 国家教委留学回国人员启动基金!(编号 990 4) 广东省科学基金!(编号 990 6)资助
关键词 牙槽缺损 四环素骨诱导活性材料 修复 实验研究 tetracycline activated material for bone guided tissue regeneration bone defect repair
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  • 1刘牧菲,广岛大学齿学杂志,1997年,29卷,70页

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