肌注长托宁救治急性有机磷中毒患者副反应的观察研究

Observation of the Side-effects in Patients with Acute Organophosphorous Intoxication after the Injection of Penehyclidine Hydrochloride for Treatment

目的：通过观察肌注长托宁救治急性有机磷中毒患者副反应，提出相关对策以防治其发生。方法：观察我院165例使用长托宁救治急性有机磷中毒患者过程中出现的长托宁及注射相关的副反应．结果：肌注长托宁救治急性有机磷中毒患者副反应发生率高达903％．与注射相关反应364％，延迟反应发生率85％。结论：肌注长托宁救治急性有机磷中毒患者副反应发生率高．有部分与注射相关可以防治。

Objectives： To put forward the related measures to prevent its occurrence by the observation of the sidc-effects in patients with acute organophosphorous intoxication after the injection ofpenehyclidine hydrochloride for treatment. Method： To observe the side-effects of penehyclidine hydrochloride during the injection in 165 patients with acute organophosphorous intoxication in our hospital. Results： The occurrence rate of side-effects in patients with acute organophosphorous intoxication after the injection of penehyclidine hydrochloride up to 90.3%, that related with injection is 3.64%, and the defer reaction is 8.5%. Conclusion： The occurrence rate of side-effects in patients with acute organophosphorous intoxication after the injection of penehyclidine hydrochloride is every high. Some reaction related with injection can be prevented.