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不同护理液对减少口腔颌面外科患者手术部位感染的作用 被引量:18

Effects of different kinds of treatment solutions on reduction of postoperative surgical site infections in oral and maxillofacial surgery patients
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摘要 目的口腔颌面外科患者术后手术部位感染(SSI)中选择最有效的口腔护理液,以预防口腔手术部位感染。方法 1293例口腔内无感染灶的患者随机分为A、B、C、D 4组,A组329例用生理盐水、B组317例用0.02%呋喃西林、C组298例用0.1%聚维酮碘、D组349例用0.12%醋酸氯己定进行术前含漱,术后口内冲洗,无植入物者术后观察并随访1个月,有植入物者术后观察并随访1年,比较手术部位感染发生情况。结果 A组发生SSI 16例,感染率为4.86%,B组发生SSI 19例,感染率为6.00%,C组发生SSI 5例,感染率为1.68%,D组发生SSI5例,感染率为1.43%,与采用生理盐水组的患者比较,呋喃西林漱洗组发生的SSI差异无统计学意义;聚维酮碘、醋酸氯己定漱洗组发生的SSI更低(P<0.05);聚维酮碘和醋酸氯己定与呋喃西林比较,聚维酮碘和醋酸氯己定组发生的SSI更低(P<0.05);聚维酮碘与醋酸氯己定比较,发生的SSI差异无统计学意义;而聚维酮碘、醋酸氯己定在预防和控制口腔颌面外科患者术后SSI发生比生理盐水和呋喃西林效果更好。结论 0.1%聚维酮碘、0.12%醋酸氯己定更能降低口腔颌面外科患者的手术部位感染发生率。 OBJECTIVE To select the most effective oral treatment solution for the prevention and regulation of postoperative surgical site infections (SSI) after the oral and maxillofacial surgery. METHODS A total of 1293 cases of patients without intra-oral infections were divided into the group A, B, C, and D ; the group A was trea- ted with normal saline, the group B with 0.02% nitrofurazone, the group C with 0.1% povidone iodine,and the group D with 0.12% chlorhexidine acetate gargle before operation, and mouth rinse after operation. The patients without implants were observed after the operation and followed up for 1 month, and the patients with implants were observed after the operation and followed up for 1 year. The incidence of the surgical sites infections was compared. RESULTS The surgical site infections occurred in 16 cases in the group A with the infection rate of 4.86%, 19 cases in the group B with the infection rate of 6.00% ,5 cases in the group C with the infection rate of 1.68% ,and 5 cases in the group D with the infection rate of 1.43% ; the difference in the incidence of the surgical site infections between the patients who used physiological saline and the patients who used furacilin for rinsing was not statistically significant; the incidence of the surgical site infections was even lower in the patients who used povidone iodine and chlorhexidine for rinsing (P〈0.05) ; as compared with the patients who used and nitro- furazone, the incidence of the surgical site infections was significantly lower in the patients who used povidone io- dine and chlorhexidine acetate (P〈0.05) ; the difference in the incidence of the surgical site infections between the patients who used povidone iodine and the patients who used chlorhexidine acetate was not statistically significant. However, the effect of povidone iodine or chlorhexidine acetate on prevention and control of postoperative surgical site infections were better that of the saline or nitrofurazone. CONCLUSION The 0. 1% povidone-iodine and 0.12% chlorhexidine acetate are more effective in reducing the incidence of surgical site infections in the patients affter the oral and maxillofaeial surgery.
出处 《中华医院感染学杂志》 CAS CSCD 北大核心 2013年第7期1577-1579,共3页 Chinese Journal of Nosocomiology
关键词 护理液 颌面外科 手术部位感染 降低 Treatment solution Oral and maxillofacial surgery Surgical site infection Reduction
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