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全身炎症反应综合征动物模型中降钙素原浓度与甲状腺激素水平相关性研究 被引量:2

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摘要 目的:制作全身炎症反应综合征(SIRS)Wistar大鼠动物模型,探讨SIRS动物模型中降钙素原和甲状腺激素的浓度水平的相关性。方法:用不同剂量的内毒素腹腔注射法,造成全身炎症反应综合征模型,观察记录呼吸、心率、体温变化,测定血中甲状腺激素与降钙素原的浓度。结果:注射内毒素的大鼠降钙素原浓度升高,甲状腺激素水平降低,体温、脉搏、呼吸频率等生命体征出现变化,大剂量内毒组变化明显。结论:全身炎症反应综合征大鼠模型中炎症反应越明显,血清降钙素原浓度越高,甲状腺激素浓度越低。预后越差。
作者 曾建慧 宗强
出处 《中外医学研究》 2013年第10期137-137,共1页 CHINESE AND FOREIGN MEDICAL RESEARCH
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