摘要
如何改善难溶性药物溶出度和口服生物利用度,业已成为药剂学研究的重点,而将其制成固体分散体,作为一种行之有效的改善方法,备受关注。综述近年来用于制备难溶性药物固体分散体的新型载体材料和新技术的研究进展。
It has been the focus of research in pharmaceutics how to improve the dissolution and oral bioavailability of poorly soluble drugs. The solid dispersion（ SD）, one of the formulation strategies to over-come this problem, has attracted much attention. The advances in new carrier materials and new techniques for the preparation of SDs of poorly soluble drugs in recent years were reviewed.
出处
《药学进展》
CAS
2013年第4期166-173,共8页
Progress in Pharmaceutical Sciences
关键词
固体分散体
难溶性药物
载体材料
制备方法
solid dispersion
poorly soluble drug
carrier material
preparation method
