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支气管哮喘持续高凝状态及抗凝治疗的效果 被引量:1

hypercoagulable state and the effect of anticoagulant therapy for bronchial asthma
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摘要 目的:分析支气管哮喘持续高凝状态及抗凝治疗效果。方法:选取2011年4月至2012年4月期间住院收治的支气管哮喘患儿86例作为研究对象,所有患儿均经临床确诊,根据治疗方法不同分为常规治疗的对照组及常规治疗联合抗凝治疗的观察组,各43例,比较两组患儿的凝血指标如凝血酶原时间(PT),凝血酶时间(TT),活化部分凝血酶时间(APTT),纤维蛋白原(Fbg)等差异。结果:观察组患儿接受治疗后PT(15.62±3.35)s、TT(23.65±5.21)s、APTT(28.56±6.52)s、Fbg(1.76±0.82)g/L等指标明显优于对照组患儿(P<0.05)。结论:对支气管哮喘患儿给予抗凝治疗可以有效改善患儿的持续高凝状态。 Objective: To analyze the hypercoagulable state of bronchial asthma and the effect of anticoagulant treatment. Methods :86 children with bronchial asthma from April 2011 to April 2012 in our hospital were as the objects of study, all children were diagnosed clinically, and divided into control group with conventional treatment and observation group with the conventional treatment therapy combined with anticoagulant therapy,43 cases in each group. Coagulation parameters such as prothrombin time (PT), thrombin time (Tr), activated partial thromboplastin time (APTT), fibrinogen (Fbg) and other differences were compared. Results:After treatment, PT( 15, 62 ± 3.35 )s, TF (23.65 ± 5.21 )s, APTT( 28.56 ±6. 52 ) s, Fbg( 1.76 ± 0. 82 ) g/L were significantly better in the observation group than those in the control group ( P 〈 0. 05 ). Conclusions: Givng anticoagulant therapy in children with bronchial asthma can be effective in improving sustained hypercoagulable state.
出处 《航空航天医学杂志》 2013年第5期525-527,共3页 Journal of Aerospace medicine
关键词 支气管哮喘 高凝 抗凝 bronchial asthma hypercoagulable anticoagulant
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