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重症患者贫血的研究进展 被引量:1

Advances in Anemia of Critical Patients
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摘要 贫血是重症患者的常见问题,其病因是多因素的,主要包括各种原因导致的急性、非急性血液丢失;此外,炎症也会导致机体红细胞寿命缩短、红细胞生成减少。针对重症患者贫血的治疗,如各种止血药物(抗纤溶剂、去氨加压素、重组Ⅶa因子等)、红细胞生成素、血液替代品(全氟化碳、改良血红蛋白等)已被应用于临床或处于临床试验阶段,相关的血液保护策略的提出也为重症患者贫血提供了一个新的防治措施,是目前广大临床医师较为关注的问题。 Anemia of critical illness is common among intensive care unit patients. The causes are multifactorial and the major reason include the acute and non-acute blood loss;in addition, inflammation can lead to shortened life of the body's red blood cells and decreased red blood cells production. For the treatment of patients with anemia, various hemostatic drugs ( antifibrinolytie agent, 1-deamino-8-D-arginine vasopressin, recombinant factor Vlla) , erythropoietin and blood substitutes (perfluoroearbon, improved hemoglobin )have been used in clinical or in clinical trials. Blood conservation strategies provides a new control measure for the patients, which is more concerned by the clinicians.
出处 《医学综述》 2013年第9期1630-1632,共3页 Medical Recapitulate
关键词 重症患者 贫血 血液保护 Critical patients Anemia Blood conservation
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参考文献26

  • 1Vincent JL,Baron JF,Reinhart K,et al. Anemia and blood transfu-sion in critically ill Patients[J]. JAMA,2002,288(12) :1499-1507.
  • 2Corwin HL,Gettinger A,Pearl RG,et al. The CRIT Study; Anemiaand blood transfusion in the critically ill_current clinical practicein the United States[ J]. Crit Care Med,2004,32( 1) :39-52.
  • 3封秀琴,朱祎容,梁皎,鲁海飞,陈建裕.ICU危重患者诊断性失血及其血液保护的研究进展[J].中华护理杂志,2007,42(12):1135-1137. 被引量:24
  • 4Lucchi L,Bergamipj S,Iannone A,et al. Erythrocyte susceptibilityto oxidative stress in phronic renal failure patients under differentsubstitutive treatn?)en-s[ J]. Artif Organs,2005,29( 1) :67-72.
  • 5Babitt JL,Lin HY. Molecular mechanisms of hepcidin regulation:implications for the anemia of CJCP[ J] . Am J Kidney Dis,2010,55(4):726-741.
  • 6Eleftheriadis T, Liakopoulos V, Antoniadi G, et al. The Role ofhepcidin in iron homeostasis and anemia in hemodialysis patients[J]. Semin Dial,2009,22( 1) :70-77.
  • 7Yoo YC, Shim JK, Kim JC, et al. Effect of single recombinanthuman erythropoietin injection on transfusion requirements in pre-operatively anemic patients undergoing valvular heart surgery [ J].Anesthesiology,2011,115(5) :929-937.
  • 8Thomas J,Jensen LtNahimiak S,et al. Anemia and blood transfu-sion practices in the critically ill:a prospective cohort review[J].Heart Lung,2010,39(3) :217-225.
  • 9Marik PE,Corwin HL. Efficacy of red blood cell transfusion in thecritically ill : a systematic review of the literature [ J]. Crit CareMed,2008,36(9) :2667-2674.
  • 10Fernandez R,Tubau I,Masip],et .al. Low reticulocyte hemoglobincontent is associated with a higher blood transfusion rate in critical-ly ill patients : a cohort study [ J]. Anesthesiology ,2010 ,112(5):12114215.

二级参考文献27

  • 1Rickard CM,Couchman BA,Schmidt SJ,et al. A discard volume of twice the vascular line deadspace ensures clinically accurate arterial blood gases and electrolytes and prevents unnecessary blood loss [J]. Crit Care Med,2003,31:1654-1658.
  • 2O'Hare D,Chilvers RJ. Arterial blood sampling practices in intensive care units in England and Wales[J]. Anaesthesia,2001,56:568-571.
  • 3Schmitz BD,Shapiro BA. Capnography[J]. Respir Care Clin N Am, 1995,1:107-117.
  • 4Jubran A,Tobin MJ. Monitoring during mechanical ventilation[J]. Clin Chest Med, 1996,17:453-473.
  • 5Peruzzi WT,Parker MA,Lichtenthal PR,et al. A clinical evaluation of a blood conservation device in medical intensive care unit patients[J]. Crit Care Med,1993,21:501-506.
  • 6Ray JG,Hamielec C,Mastracci T. Pilot study of the accuracy of bed-side glucometry in the intensive care unit[J].Crit Care Med,2001,29:2205-2207.
  • 7Salem M,Chernow B,Burck R,et al. Bedside diagnostic blood testing: Its accuracy,rapidity,and utility in blood conservation [J].JAMA, 1991,266:382-389.
  • 8Alex CP,Manto JC,Garland JS. Clinical utility of a bedside blood analyzer for measuring blood chemistry values in neonates[J]. J Perinatol, 1998,18:45.48.
  • 9Papadea C,Foster J,Grant S,et al. Evaluation of the i-STAT portable clinical analyzer for point-of-care blood testing in the intensive care units of a university children's hospital[J]. Ann Clin Lab Sci,2002,32:231-243.
  • 10Poller L,Keown M,Chauhan N,et al. Reliability of international nor-malized ratios from two point of care test systems:Comparison with conventional methods[J]. BMJ,2003,327:30-35.

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