摘要
目的观察恩度联合多西紫杉醇川l页铂方案治疗原发灶不明癌的近期疗效及毒副作用。方法12例未经治疗的临床诊断原发灶不明癌患者给予恩度联合多西紫杉醇+顺铂方案,观察其近期疗效及毒副作用。结果12例总有效率为58.3%,疾病控制率为91.7%,毒副作用主要为血液学毒性、脱发及恶心/呕吐,未出现IV期毒副作用,无一例患者死于化疗毒副作用。结论恩度联合多西紫杉醇+顺铂方案治疗原发灶不明癌有效提高了化疗的有效率,且不良反应可以耐受。
Objective To observe the efficacy and toxicity of endostar combined with chemother- apy for the treatment of unknown primary cancer. Methods Twelve patients with clinical diagnosis of unknown primary cancer were given endostar combined docetaxel + eisplatin. Then the efficacy and tox- icity was observed. Results The overall effective rate was 58.3%, the disease control rate was 91.7%. The mainly toxicity was hematologic toxicity, alopecia and nausea/vomiting, without stage IV toxicity, no patients died from the adverse reations of chemotherapy. Conclusions Endostar combined with docetax- el + cisplatin in the treatment of unknown primary cancer patients improve the chemotherapy effectively, and the toxicity can be tolerated.
出处
《中国实用医刊》
2013年第11期51-52,共2页
Chinese Journal of Practical Medicine
关键词
原发灶不明癌
恩度
化疗
Unknow primary cancer
Endostar
Chemotherapy