重症肺炎影响极低出生体重儿血小板及凝血功能的研究

Research on Severe Pneumonia Influence Platelet and Blood Coagulation Function of Very Low Birth Weight Babies

目的:通过观察我院收治的极低出生体重新生儿肺炎的临床治疗,研究重症肺炎对该类疾病患儿的血小板及凝血功能的影响,探讨其临床研究价值。方法:将47例一般肺炎的极低出生体重新生儿设为对照组,45例重症肺炎的极低出生体重新生儿设为实验组,对比分析两组患儿的血小板参数的检测指标并行患儿凝血功能检查。结果:在血小板参数方面,实验组在MPV和PDW的数据较对照组高,而在PLT明显较低;在凝血功能方面,实验组在PT、APTT和TT等方面的数据较对照组高,而在FIB方面明显较低。结论:临床上对动态监测重症肺炎患儿血小板的变化情况,对判断该疾病患儿的预后具有积极的参考与预警意义,而对重症肺炎患儿出现凝血系统功能紊乱及时把握具体发病机制,对症进行凝血功能恢复治疗,值得临床进一步研究与探讨。

Objective： Through observing clinical treatment of very low birth weight newborn with pneumonia,the clinical research value of severe pneumonia influence platelet and blood coagulation function of birth weight was discussed.Methods： 47 very low birth weight newborn with general pneumonia were set as the control group,45 very low birth weight newborn with severe pneumonia were set as the experimental group,a comparative analysis of the two groups of children with platelet parameters testing index parallel with coagulant function check.Results： Results Compared with control group,the MPV and PDW data of the experimental group is Significantly higher than the control group and the PLT data is Significantly lower in terms of platelet parameters.In the function of blood coagulation,the data of PT,APTT and TT of the experimental group is higher than the control group,but was significantly lower in FIB.Conclusions： The dynamic monitoring of platelet count dynamic change of the babies with severe pneumonia,has positive reference and warning significance to judge the prognosis of children with the disease,and for children with severe pneumonia in blood coagulation system dysfunction should be timely grasp the specific nosogenesis,suit for blood coagulation function recovery treatment,it is worth further clinical research and discussion.