摘要
目的:观察三七接骨丸促进胫骨瓣切取术后骨缺损修复的临床疗效。方法:胫骨瓣切取术后的60例患者按照入院顺序随机分为治疗组和对照组,每组30例。在胫骨骨瓣切取术后,治疗组予以三七接骨丸,水冲服,每次6g,1d2次;对照组给予骨肽片,每次2粒,1d3次;疗程各6周。于胫骨骨瓣切取术后4、10、16、24周摄供区X线片。根据参照Saman-tha等评分标准对骨缺损愈合进行评分,从服药后开始分别观察2组疼痛消失最短时间;用药后第3、6、9、12天观察肿胀情况。结果:术后第3天肿胀情况比较两组差异无统计学意义(P>0.05),而术后第6天两组肿胀情况比较差异有统计学意义(P<0.05),第9、12天患肢肿胀情况基本与第6天情况相同。治疗组比对照组能明显缩短患者的疼痛时间,治疗组患者自觉疼痛消失的时间比对照组缩短1.1d,差异有统计学意义(P<0.01)。术后第4周供区骨缺损骨痂生长情况差异有统计学意义(P<0.05),第10、16、24周患肢骨痂生长情况与第6周情况基本相同,各个时期治疗组均明显优于对照组(P<0.05)。结论:三七接骨丸能够明显消除骨折术后肿胀,缩短疼痛时间,促进骨折愈合,是临床修复骨缺损的有效药物。
Objective:To observe the effects of Sanqi Jiegu Pill on promoting the repair of bone defects after tibial bone flap resection. Methods:Sixty patients who underwent tibial bone flap resection were randomly divided into treatment group and control group, 30 in each group. In the treatment group, patients were given Sanqi Jiegu Pill 6g once, twice a day, while patient's in control group were given ossotide tablets 2 tablets once, three times a day. The treatment lasted 6 weeks. At week 4, 10, 16, and 24 after tibial bone flap resection, X-ray examination was performed to assess the healing of bone de- fects according to Samantha standard. The time for the pain to disappear was recorded. At day 3, 6, 9, and 12 after drug administration, swelling condition was observed in the two groups. Results:There was no significant difference in swelling condition between the two groups after 3-day treatment (P〉 0.05). From the 6th day on, remarkable difference was found between the two groups in swelling condition (P〈0.05). The time for the pain to disappear was 1.1 days shorter in treat- ment group than the control group, showing significant difference between the two groups (P〈0.05). From the 4th week after surgery, there was significant difference in callus growth between the two groups (P〈0.05). There was similar con- dition for the 10th, 16th, and 24th week. Conclusion:Sanqi J iegu Pill can significantly ameliorate the swelling, shorten the time of pain, and promote bone healing, thus effective for repair of bone defects.
出处
《中国中医骨伤科杂志》
CAS
2013年第8期21-23,共3页
Chinese Journal of Traditional Medical Traumatology & Orthopedics
关键词
三七接骨丸
胫骨瓣
骨缺损
修复
Sanqi Jiegu Pill
tibial bone flap
bone defects
repair