氧氟沙星注射液细菌内毒素检测方法探讨

Method for Determining Bacterial Endotoxin in Ofloxacin Injection

目的:有鲎试剂检测氧氟沙星注射液的内毒素 方法:参照中国药典1995年版二部收载的细菌内毒素检查方法进行检测 结果:氧氟沙星注射液中细菌内毒素用标示值灵敏度为0.25EU·ml^1检测有效

Aim: To test bzacterial endotosin in ofloxarin injectio with TAL TAL reagent. Method: The bacterial endotoxin ofloxacin injection according to Pharmacopoeia of the People's Republic of China 2000. Result: The bacterial endotoxin in ofloxacin injection could be effectively determined with the marker value 0. 25KU/ml as sensitivity. Conclution: The rabbit method can be replaced by TAL reagent method to determine the pyrogen in ofloxacin injection.