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降钙素原在细菌感染所致慢性阻塞性肺疾病急性加重诊治中的研究进展 被引量:6

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摘要 慢性阻塞性肺疾病(chronicobstructivepulmonarydis—ease,COPD)是一种常见、逐渐加重的疾病,在美国主要导致死亡的疾病中位列第4,并有逐渐上升的趋势。绝大部分中、重度COPD会经历急性加重(acuteexacerbationchronicob—structivepulmonarydisease,AECOPD),AECOPD常伴不同程度的不良后果,包括:生活质量下降、肺功能减损、严重者甚至会引起死亡,患者还需承担更高的社会经济负担。约25%~50%的AECOPD是由细菌感染导致的,尽管抗菌药物的使用在减少病死率和治疗失败率等方面大有益处,而欧美有约85%的AECOPD使用了抗菌药物治疗,这个比例显然高于细菌导致AECOPD所应使用的抗菌药物比例。
出处 《重庆医学》 CAS CSCD 北大核心 2013年第27期3310-3313,共4页 Chongqing medicine
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