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青霉素类药物不良反应报告分析 被引量:9

Analysis of adverse reaction reports of penicillin drugs
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摘要 目的比较注射与口服青霉素类药物不良反应的差别。方法采用回顾性分析方法对2007~2012年江苏省不良反应中心收集到的青霉素类药品的不良反应报告进行分析。结果江苏省注射用青霉素的不良反应数为6 082例,占92.98%;口服青霉素的不良反应数为454例,占6.94%。注射用青霉素有新的严重的不良反应2例。注射用青霉素不良反应病例经治疗后有9例死亡病例,3例病人留下后遗症;口服青霉素的不良反应经治疗后均痊愈或好转。结论口服青霉素类药物不良反应数量少,且严重程度低,经治疗后无死亡或留下后遗症的病例。 Objective Compare with injection penicillin drugs and oral penicillin drugs for ADR.Method The adverse reaction reports of penicillin drugs collected by Jiangsu adverse reaction center from 2007to 2012were analyzed retrospectively.Result The case number of adverse reactions of injection penicillin was 6 082,accounting for 92.98%;Oral penicillin adverse reactions number was 454cases,accounting for 6.94%;The injection penicillin drugs had new serious adverse reactions in 2cases;After the treatment of injection penicillin adverse reaction,9cases were die and 3cases left sequela;On the other hand,the cases of oral penicillin adverse reactions were recoveried or better after treatment.Conclusion For the adverse drug reactions of oral penicillin,the quantity was less and the serious degree was low and no death or sequela was reported after treatment.
出处 《西北药学杂志》 CAS 2013年第5期524-526,共3页 Northwest Pharmaceutical Journal
关键词 青霉素 不良反应报告 变态反应 分析 penicillin adverse reaction reports allergic reaction analysis
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