顺尔宁治疗及预防支气管哮喘的疗效观察

To observe the effect of Singulair prevention and treatment of bronchial asthma

目的观察顺尔宁治疗及预防儿童支气管哮喘的临床疗效。方法将52例支气管哮喘患儿随机分成治疗组30例和对照组22例,治疗组采用顺尔宁口服,对照组给予布地萘德气雾剂吸入,两组总疗程均为3个月,停药后随访6个月,观察治疗效果及复发情况。结果两组疗效比较,治疗组总有效率(96.7%),明显优于对照组(68.2%),差异有统计学意义(P<0.05);两组患儿发作次数、住院次数、PET比较,差异有统计学意义(P<0.05)。结论采用顺尔宁治疗及预防支气管哮喘,可以明显减少患儿复发及住院次数,控制和减轻症状,疗效确切,未见任何不良反应。

Objective To observe the clinical efficacy of montelukast tor the treatment and prevention ot bronchial asthma in children. Methods All of 52 patients with bronchial asthma were randomly divided into treatment group 30 cases and control group 22 cases, the treatment group treated with Singnlair oral, control group were given Budesonide aerosol inhalation, two groups were treated for 3 months, after discontinuation of follow-up of 6 months, to observe the therapeutic effect and recurrence. Results The results of the two groups curative effect, the total effective rate of treat- ment group （96.7%）, significantly better than the control group （68.2%）, the difference was statistically significant （P 〈 0.05）, two groups of children with attack frequency, frequency of hospitalization, PET comparison, the difference were statistically significant （P 〈 0.05）. Conclusion Singulair prevention and treatment of bronchial asthma, can significant- ly reduce the relapse in children and the times of hospitalization, control and reduce the symptoms, curative effect, no adverse reaction.