摘要
目的 观察诺维本 (NVB) +吡喃阿霉素 (THP)联合治疗晚期乳腺癌疗效。方法 NVB+THP联合治疗 31例晚期乳腺癌 ,均为女性 ,其中Ⅲ期 18例 ,Ⅳ期 13例。结果 本组 31例完全缓解 (CR) 3例 ,部分缓解 (PR) 16例 ,有效率为 61 3%。主要毒付反应 ,是骨髓抑制或静脉炎 ,白细胞下降为 93 2 %,其中Ⅲ、Ⅳ度为 50 2 %,静脉炎发生率为 4 2 0 %。结论 NVB +THP联合治疗乳腺癌 ,有效率较高 ,但骨髓抑制发生率高 ,必须引起重视。
Objective To evaluate the combined chemotherapy efficacy and toxicity of NVB and THP on advanced breast cancer.Methods All the 31 patients were treated with NT regimen NVB 25mg/M2 iv for Day 1 and 8;THP 45mg/m2 iv for Day 1.Results Complete response was 3 cases,Partial response 16 cases,the overall response rate was 61.3%. Side reactions were mainly myelosuppression and phlebitis.Conclusion The NT regimen is a better chemotherapy regimen for advanced breast cancer.
出处
《肿瘤防治研究》
CAS
CSCD
北大核心
2000年第6期470-471,共2页
Cancer Research on Prevention and Treatment
