细胞因子与角膜新生血管形成研究进展

Progress of formation of corneal neovascularization and cytokines

角膜新生血管(CNV)是许多眼科疾病的常见并发症,不但严重影响视力,也是角膜移植排斥反应发生的高危因素。研究CNV发病机制和寻找能阻止其形成的抑制剂,将对防盲治盲、提高CNV患者的生存质量具有极其重要的意义。现在认为,CNV的形成与多种细胞因子的调控密切相关。现就参与CNV形成的主要细胞因子的研究进展情况作一综述。

Corneal neovascularization （CNV） is a common complication of many eye disease,which not only seriously affect vision,but also is high risk factors of corneal graft rejection reaction.It is important to prevent blindness and improve the quality of CNV patient survival that research on the mechanism of CNV and looking for the inhibitors to prevent the formation of CNV.Now we believe that CNV formation is closely related to a variety of regulating cell factors.We will review the main research progress of cytokines that assosiated with the formation of CNV.