恶性胸腔积液治疗的研究进展

Research Progress in Treatment of Malignant Pleural Effusion

恶性胸腔积液(MPE)是恶性肿瘤通过直接或间接侵犯胸膜或胸膜原发性肿瘤所致。患者以MPE为首发症状或恶性肿瘤进展并发胸腔积液,往往提示病情已处于晚期,生存期仅4个月左右。大量胸腔积液可导致压迫性肺不张、限制性通气障碍、甚至呼吸衰竭,严重影响患者的呼吸循环功能,威胁患者生命。因此,采取积极有效的治疗措施以缓解患者症状、提高患者生存质量,显得尤为重要。

Malignant pleural effusion （MPE）is caused by direct or indirectly violation to the pleura or pleura/primary tumor from malignant tumors. Patients with malignant pleura/effusion as the first symptom or pleura/ effusion combined with malignant progression, often indieate the disease has been in the late stage, and the survival period is only four months or so. Large pleural effusion can cause compressive ateleetasis, restrictive ventilatory defect, or even respiratory failure, seriously impacting the patient＇s respiratory and circulatory function, threatening the lives of patients. Therefore it is particularly important to take positive and effective treatment measures to relieve symptoms and improve the patient＇s quality of life.