彩色多普勒超声诊断糖尿病患者颈动脉粥样硬化斑块形成的临床价值

Clinical value of color Doppler ultrasound in diagnosis of carotid atherosclerotic plaque formation in patients with diabetic

目的探讨彩色多普勒超声诊断糖尿病患者颈动脉粥样硬化斑块的临床价值。方法选择本院2008年8月～2013年4月收治的糖尿病患者80例作为观察组。选择同期本院体检中心的健康体检人员80例（无高血压、糖尿病、冠心病等疾病）作为对照组。应用西门子X300型彩色多普勒超声诊断仪检测两组有无斑块形成及斑块形态大小．观察颈总动脉内径、颈总动脉内膜一中层厚度，测量血管阻力指数。结果观察组斑块发生率为63．75％（51／80），显著高于对照组的26．25％（21／80），差异有统计学意义（P〈0．01）。观察组颈总动脉内膜-中层厚度显著大于对照组，差异有统计学意义（P〈0．01）；颈总动脉内径及血管阻力指数与对照组比较，差异无统计学意义（P〉0．05）。结论彩色多普勒超声检测糖尿病患者颈动脉粥样硬化斑块形成有重要的临床价值，对糖尿病患者并发症的防治具有重要的意义。

Objective To explore the clinical value of color Doppler ultrasound in diagnosis of carotid atherosclerotic plaque in patients with diabetic.Methods 80 patients with diabetes treated in hospital from August 2008 to April 2013 were selected as the observation group,80 cases of healthy volunteers （without hypertension,diabetes,coronary heart dis- ease） in hospital medical center at the same period were selected as the control group.Siemens X300 color Doppler ul- trasonography were used to detect whether the size of plaque formation and plaque morphology,carotid artery diameter, carotid artery intima-media thickness was observed,vascular resistance index was measured.Results The incidence of plaque in the observation group was 63.75% （51/80）,which was significantly higher than 26.25% （21/80） of the control group,the difference was significarlt （P〈0.01）.The carotid artery intima-media thickness of the observation group was significantly thicker than that of the control group,the difference was significant （P〈0.01）; common carotid artery diam- eter and vascular resistance index compared to the control group,the difference was not significant （P〉0.05）.Conclusion Color Doppler ultrasound has important clinical value for detection of carotid atherosclerotic plaque formation in diabetic patients,which is of great importance for prevention and treatment of complications in diabetic patients.