摘要
为研究党参多糖口服液的抗应激与抗炎作用,给小鼠灌服不同剂量(每kg体重灌服9、7、5 g生药)的党参多糖口服液后,通过测定小鼠负重游泳时间、常压耐缺氧时间来评价其应激性作用;观察党参多糖口服液对小鼠耳廓二甲苯致炎的影响,考察其抗炎作用。结果显示,党参多糖口服液能显著(P<0.01)延长小鼠的游泳时间和常压缺氧条件下的存活时间,对二甲苯所致小鼠耳廓炎症具有不同程度的抑制作用。因此,党参多糖口服液具有抗应激、抗炎作用,该试验可为党参多糖口服液的临床应用提供参考。
After the mouse are feed different dosages of Codonopis pilosula polysaccharide oral liquids (5 g crude drug/kg, 7 g crude drug/kg, 9 g crude drug/kg), their role of stress is evaluated by the time of loaded swimming and hypoxia tolerance, and their anti - inflammatory effect is investigated by the influence of inflammatory of mouse' s ear, induced by xylene. The result is that the Codonopis pilosula polysaccharide oral liquids (P 〈 0. 01 ) can outstanding prolongs the time of swimming of mouse and survival in the conditions of atmospheric pressure and hypoxia, and the inflammation of mouse' s ears, induced by xylene, is restrained with different levels. Those prove that the Codonopis pilosula polysaccharide oral liquids have apparent function of anti - stress and anti - inflammatory. This research can provide a reference for the clinical uses of Codonopis pilosula polysacehafide oral liquids.
出处
《中国兽药杂志》
2013年第11期37-39,共3页
Chinese Journal of Veterinary Drug
关键词
党参多糖口服液
应激性
抗炎作用
小鼠
Codonopsis pilosula polysaccharide oral liquids
stress ability
anti - inflammatory effects
mice