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cTnI和NT-proBNP联合检测在急性心肌梗死诊断中的应用 被引量:8

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摘要 目的探讨心肌肌钙蛋白I(cTnI)、氨基末端B型利钠肽前体(NT-proBNP)联合检测在急性心肌梗死(AMI)诊断中的应用。方法选择首发AMI患者68例,将其作为AMI组,另选择于68例健康中、老年人作为对照组。对照组健康者抽清晨空腹肘静脉血3mL,AMI组患者于入院后即刻抽肘静脉血3mL,采用Mini-Vidas-Blue全自动荧光免疫分析仪及其配套原装试剂进行血清cTnI和NT-proBNP检测,以NT-proBNP>300pg/mL、cTnI>0.01μg/L为异常结果。结果 AMI组患者血清NTproBNP、cTnI的检测结果均明显高于对照组(P<0.05)。AMI组血清NT-proBNP与cTnI呈正相关(r=0.835,P<0.05)。NTproBNP、cTnI联合检测,其诊断敏感性和特异性分别达99.6%、98.5%,与单独检测比较,差异有统计学意义(P<0.05)。结论 NT-proBNP、cTnI联合检测可提高AMI诊断的敏感性和特异性。
作者 张志强
出处 《国际检验医学杂志》 CAS 2013年第23期3241-3242,共2页 International Journal of Laboratory Medicine
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