补肾活血中药对椎体成形术后患者的视觉模拟评分及骨密度的影响

Effect of Chinese Medicine for Reinforcing Kidney and Activating Blood on Visual Analogue Scale and Bone Density in Patients of Post Vertebroplasty

目的:观察补肾活血中药对椎体成形术(PVP)后患者临床症状改善的促进作用。方法:选择确诊为骨质疏松性椎体压缩性骨折的96例患者,均采用标准的PVP手术,根据患者术后是否服用补肾活血中药将其分为:A组48例为治疗组(口服补肾活血中药+钙剂);B组48例为对照组(口服钙剂)。分别于术后3个月、6个月、12个月应用视觉模拟评分(VAS)和骨密度来评价患者疼痛改善及骨质改变情况。结果:所有患者均顺利完成手术,术后患者疼痛均得到迅速缓解。术后3个月、6个月和12个月两组患者VAS评分、骨密度均较术前有明显改善(P<0.05)。组间比较发现,术后3个月时VAS评分、骨密度差异无显著性(P>0.05);但术后6个月及术后12个月时两组间VAS评分、ODI评分比较差异有显著性(P<0.05)。结论:PVP是治疗骨质疏松性椎体压缩骨折的有效方法,同时,术后口服补肾活血中药可对患者的疼痛缓解和骨质改善起促进作用,随着用药时间的延长,作用越明显。

Objective：to observe the promotive effect of Chinese medicine for reinforcing kidney and activating blood on patients of post PVP.Methods：94 patients with osteoporosis-induced compression fracture of vertebral body , after standard PVP, were divided, according to whether they took medicine , into two groups , group A （ treatment group taking orally the medicine and calcium ） and group B （ control group taking calcium ） .Visual analogue scale （ VAS） and bone density were used to evaluate the pain improvement and sclerotin changes respectively 3, 6 and 12 months after operation.Results：All the patients were operated on smoothly and the pains were quickly relieved.All the tested indexes were improved significantly （ P 〈0.05） .Comparisons between groups showed that there was on significant difference about VAS and bone density 3 months after operation （ P 〉0.05 ） , but there were significant difference a-bout VAS and ODI 6 and 12 months after operation （ P 〈0.05） .Conclusion：PVP is an effective way in curing osteoporosis-induced compression fracture of vertebral body and meanwhile Chinese medicine for reinforcing kidney and activating blood can relieve pain and improve the sclerotin.The longer the medication is , the more obvious the action will be.