精神科住院患者白细胞变化与医院内感染

The relationship between WBC changes and nosocomial infection in patients with mental disorders

目的 :了解精神科患者住院期间白细胞 (WBC)变化与医院内感染 (NI)的关系。 方法 :调查 1996年 3月～ 1999年 2月精神科出院病历。将感染前 2周内或住院期间 WBC<5 .0× 10 9/L列为 A组 ,≥ 5 .0× 10 9/ L列为 B组 ,研究其感染率和人均感染日的差异。 结果 :调查 6 6 7份出院病历 ,医院内感染率 2 6 .7% ;A组感染发生率 (6 4.8% )远高于 B组 (2 0 .7% ) (P<0 .0 0 5 ) ;NI患者人均感染日 A组 (15 .4± 2 .1天 )也高于 B组 (10 .3± 1.2天 ) (P<0 .0 5 ) ,均有显著差异。 结论 :精神科住院患者 WBC<5 .0× 10 9/ L 时 。

Objective:To study the relationship between WBC changes and nosocomial infection in patients with mental disorders. Method:The medical records of discharged patients who had been admitted in the department of mental disorders from 3, 1996 to 2, 1999 were reviewed. During two weeks before infection or during hospitalization, these patients were divided into two groups according to WBC value: group A <5 0×10 9/L, group B ≥5 0×10 9/L. The infection rate, difference of mean infection days and the pattern of WBC changes in different periods were studied. Results:In terms of 667 medical records, the nosocomial infection rate was 26 7%, in which the infection rate of group A (64 8%) was far more higher than that of group B (20 7%) ( P <0 005), and the mean infection days of group A (15 4±2 1 days) was also more than that of group B (10 3±1 2 days) ( P <0 05). Conclusion:The patients in department of mental disorders, whose WBC value is less than 5 0×10 9/L, are susceptible to suffer the nosocomial infection.