摘要
目的:观察三七花总皂苷对自发性高血压大鼠(SHR)血压、心率的影响。方法:以SHR为研究对象,ACL-NIBP鼠尾无创血压测量分析系统录给药前后血压及心率的变化。结果:三七花总皂苷对SHR收缩压、舒张压有一定降低作用(P<0.05,P<0.01),存在剂量相关性,但对心率影响小。结论:七花总皂苷对SHR大鼠具有降低血压作用。
Objective:To study the influence of panax notoginseng flower saponins (PNFS) on blood pressure and heart rate of spontaneous hypertension rats (SHR). Methods:Blood pressure and heart rate of the rats were recorded and calculated respectively by ACL - NIBP system before and after PNFS treatment. Results : Systolic pressure and diastolic pressure were declined significantly (P 〈 0. 05, P 〈 0.01 ), while the heart rate had no significant changes (P 〉 0. 05 ). Conclusion: PNFS can down regulate blood pressure in spontaneous hypertension rats significantly.
出处
《中华中医药学刊》
CAS
2014年第2期367-369,共3页
Chinese Archives of Traditional Chinese Medicine
基金
上海市高新技术产业科技开发基金项目(沪创新J-58)
关键词
三七花总皂苷
自发性高血压大鼠
panax notoginseng flower saponins
spontaneous hypertension rat