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四川西北地区老年冠心病与血浆同型半胱氨酸的相关性观察 被引量:9

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摘要 目的 研究川西北地区老年冠心病与血浆同型半胱氨酸(Hcy)的相关性.方法 对581例可疑冠心病的老年患者行冠脉造影,分为冠心病组和造影正常的对照组,冠心病组分为稳定性心绞痛(SAP)组和急性冠脉综合征(ACS)组.以Gensini积分评价冠状动脉病变程度,测定血浆Hcy、血糖、血清肌酐(Cr)、胆固醇(TC)、甘油三酯(TG)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)、血清叶酸、维生素B12和维生素B6水平.分析血浆Hcy与年龄、Gensini积分、血糖、Cr、TC、TG、HDL-C、LDL-C、血清叶酸、维生素B12和维生素B6水平的关系.结果 血浆Hcy随年龄的增长而显著升高;与对照组相比,SAP组和ACS组Hcy水平均升高显著,且ACS组较SAP组升高明显,血浆Hcy随着Gensini积分的增加而升高;血浆Hcy致冠心病的优势比(OR)为2.3431,其95%的可信限1.6691~4.9324.结论 血浆Hcy是导致四川西北地区老年冠心病的独立危险因素.
出处 《中国医刊》 CAS 2014年第1期49-51,共3页 Chinese Journal of Medicine
基金 四川省医学会基金课题(SHD11-11)
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