脐疗糊剂制剂学研究进展

Research progress of pharmaceutics for ointments in navel therapeutic

脐疗是具有鲜明中医特色的疗法,脐疗剂型包括多种,文章介绍糊剂。糊剂的润湿剂包括单一介质和混合介质。目前应用的脐疗糊剂优点是润湿剂容易获得,制备简便,适合家庭和医院小规模制备;缺点是药物容易脱落,污染衣物;目前糊剂脐疗中促进药物渗透的技术包括使用渗透促进剂、脐疗前拔罐或局部揉搓脐部、提高药物和皮肤温度等。可设计新型的脐疗糊剂以提高透皮吸收和患者的顺应性。

The dosage forms used in navel included several kinds, the topic of this article was ointment. The wetting agents in ointment contained single medium and complex mediums. Merits of current ointments used in clinic were the easily gainable for wetting agems, simple to be prepared, and current ointments were suit for preparing at home and in hospital. Shortcomings of present ointments included that drugs in the ointment tended to escape from the equipments, and polluted the clothes. The technologies that have been applied in navel therapy in ointment contained using permeation enhancer, cupping or kneading navel before navel therapy, raising the temperature of the skin and the ointment. New navel therapeutic ointment should be designed to be more penetrative and more compliant for patients.