Construction of the recombinant retroviral vector encoding anti-HCC single-chain bifunctional antibody and establishment of a stable virus producing PA317 cell line
1Taylor N, Bacon K B, Smith S, et al. Reconstitution of T Cell Receptor Signaling in ZAP-70-deficient Cells by Retroviral Transduction of the ZAP-70 Gene[J]. J Exp Med, 1996,184(5): 2031-2036.
2Rosenberg C. Gene therapy researcher under fire over controversial cancer trials[J]. Nature, 1992, 360(6403): 339-400.
3Chaudhary V K, Batra J K, Gallo M G, et al. A rapid method of clining functional variable-regin antibody gengs in Escherichia coli as single chain immunotoxins[J]. Proc Natl Acad Sci USA, 1990,87(3):1066-1070.
4Adams G B, McMullen M, Turner S, et al. Isolation and Transduction of CD34+ Cells From Small Quantities of Peripheral Blood From HIV-1-Infected Patients Not Treated With Hemopoietic Growth Factors[J]. J Acquired Immune Deficiency Syndromes & Human Retrovirol, 1999, 21(1):1-8.
5Barzon L, Bonaguro R, Castagliuolo I, et al. Transcriptionally Targeted Retroviral Vector for Combined Suicide and Immunomodulating Gene Therapy of Thyroid Cancer[J]. J Clin Endocrinol & Metabol, 2002, 87(11): 5304-5311.
6Chen S Y, Yang A G, Chen J D, et al. Potent antitumor activity of a new class of tumour-specific killer cells[J]. Nature, 1997,385 (6611):78-80.
7Yang A G, Chen S Y. A new class of antigen-specific killer cells [J]. Nat Biotechnol,1997, 15(1):46-51.
8Mah C, Byrne B J, Flotte T R. Virus-Based Gene Delivery Systems[J]. Clin Pharmacokinet, 2002, 41(12): 901-911.
9Kellen J A. Gene therapy in cancer[J]. J Exp Therap & Oncol, 2002, 2(6): 312-316.
10Culver K, Cornetta K, Morgan R, et al. Lymphocytes as cellular vehicles for gene therapy in mouse and man[J]. Proc Natl Acad Sci USA, 1991, 88(8): 3155-3159.