水苏糖与中药组合物对患皮肤瘙痒症小鼠的药效学研究

Stachyose and the traditional Chinese medicine composition studies on efficacy of skin pruritus in mice

目的:观察水苏糖与中药组合物构成的复方对实验性皮肤瘙痒模型的影响。方法:采用右旋糖酐-40诱发小鼠皮肤瘙痒模型,测定小鼠搔痒潜伏时间及搔痒次数。结果:复方A能明显减少右旋糖酐-40所致小鼠的搔痒次数及搔痒发作的潜伏时间(P<0.01)。结论:水苏糖复方具有显著止痒作用,对实验性皮肤瘙痒具有一定的治疗作用。

Objective To observe the affection of Stachyose composite on experimental itchy skin model.Methods The incubation period and the times of itch in mice pruritus model induced by dextran 40.Results Stachyose composite A could decrease the times of itch and prolong the incubation period in mices.Conclusion Th Stachyose composite has therapeutic effect on experimental pruritus.