临床药师参与救治多脏器功能损害并巨细胞病毒感染患者的实践

Practice of Clinical Pharmacists Participating in the Treatment of Multi-organ Injury Complicating with Cytomegalovirus Infection

目的:探讨临床药师在参与救治多脏器功能损害并巨细胞病毒感染患者中的作用。方法:运用药学专业知识结合患者的实际病情,从药物的药效学、药动学和药品不良反应等方面入手,配合医师选择有效、恰当的治疗药物(喜炎平注射液),将给药间隔由qd调整为q12h,为患者A停用引发皮疹的肝舒宁注射液,为有肝肾功能损害的患者B选择泮托拉唑注射液。结果:通过临床药师和临床医师的合作救治,挽救了重症患者的生命,患者康复出院。结论:成年患者在获巨细胞病毒感染后使用喜炎平注射液可获得满意的疗效,但由于病例数少,还需临床进一步观察。

OBJECTIVE： To discuss the role of clinical pharmacists participating in the treatment of multi-organ injury compli- cating with cytomegalovims infection. METHODS： Using the knowledge of pharmacy and considering about the situation of pa- tients, clinical pharmacists helped the doctor to choose effective and appropriate drug as Xiyanping injection, adjust dosing interval of once a day to every 12 h from pharmacodynamics, phannacokinetics, adverse drug reactions and so on. patient A stopped taking Ganchuning injection which resulted in erythay, and patient B with liver and kindney function damage chose pamtoprazole injection. RESULTS： Severe patients were cured and discharged from the hospital by the cooperation of clinic pharmacist and doctor. CONCLU- SIONS： Xiyanping injection in the treatment of cytomegalovirus infection in adult patients shows satisfactory efficacy, which is still further observed in the clinic due to small number of cases.