血清PCT、CRP及乳酸在重症肺炎中的变化及临床意义

Clinical value research of serum PCT,CRP and lactic acid for patients with severe pneumonia

目的:探讨血清降钙素原(PCT)、C反应蛋白(CRP)和乳酸在重症肺炎中的变化及意义。方法:96例重症肺炎患者在入院后的第1、4、7天和转科及死亡前分别进行PCT、CRP和乳酸的检测,根据预后将96例重症患者分为死亡组和存活组来进行比较和分析PCT、CRP和乳酸的变化。结果:96例患者中死亡34例,存活62例。死亡组第4、7天的PCT值、CRP值和乳酸水平明显高于存活组,差异具有统计学意义(P<0.05)。结论:动态监测血清中的PCT、CRP和乳酸有助于判定重症肺炎的病情程度和预后,可指导临床。

Objective To explore the clinical value of proealcitonin （PCT）, C creactive protein （CRP） and lactate levels in ser- um in patients with severe pneumonia. Methods 96 cases of patients with severe pneumonia collected from January 2010 to January 2014 were divided into the death group and survival group for further compare and analysis according to the prognosis. The levels of PCT , CRP and lactate in Serum were deteceted on 1, 4, 7 days after admission . Results34 patients died, 62 patients survived in 96 cases. The levels of PCT, CRP and lactate in serum on the 4 and 7 day in death group were significantly higher than of survival group, the difference was statistically significant （ P 〈 0. 05 ）. ConclusionDynamie detection of PCT, CRP and lactate levels trend in serume was helpful for the prognosis of patients with severe pneumonia.