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血清胱抑素C对造影剂肾病的早期评估 被引量:2

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摘要 目的了解血清胱抑素C(Cys C)对冠状动脉造影患者早期肾毒性的评估价值。方法观察133例冠状动脉造影患者肾功能变化,于造影前、造影后第1天、第2天分别测定血尿素氮(BUN)、血肌酐(SCr)、Cys C、尿微量白蛋白(mALB)水平。结果在冠脉造影后第1天、第2天血清Cys C水平与造影前比较均有显著性差异(P均<0.05),造影后第2天与第1天比较有显著性差异(P<0.05)。造影后第1天、第2天BUN、SCr水平与造影前比较无显著性差异(P均>0.05),造影后第2天与第1天比较亦无显著性差异(P均>0.05);造影后第1天mALB与造影前比较有显著性差异(P<0.05),造影后第2天与造影前比较无显著性差异(P>0.05),造影后第2天与第1天比较有显著性差异(P<0.05)。结论在冠脉造影前无肾功能损害患者中未见造影后发生造影剂肾病,部分患者存在一过性轻度蛋白尿升高;血Cys C、尿mALB是反映造影剂早期肾毒性的敏感指标,但血Cys C检测的临床意义更大。
出处 《现代中西医结合杂志》 CAS 2014年第17期1859-1860,共2页 Modern Journal of Integrated Traditional Chinese and Western Medicine
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