抗生素降阶梯治疗小儿重症肺炎的效果观察

Effect observation of antibiotic step-down therapy treating severe pneumonia in children

目的分析探讨抗生素降阶梯治疗小儿重症肺炎的临床效果。方法选取本院近年来收治的80例重症肺炎患儿作为研究对象,按照数字抽签法将其随机分为研究组与对照组,每组各40例。研究组患儿行抗生素降阶梯治疗,对照组患儿行常规抗生素治疗,比较两组的治疗效果。结果研究组的治愈率为40.0%,总有效率为85.0%,对照组的治愈率为15.0%,总有效率为70.0%,研究组的治疗效果明显优于对照组(P<0.05);研究组患儿感染病症控制时长与住院时长明显短于对照组(P<0.05);两组治疗过程中并未出现严重的不良反应。结论针对小儿重症肺炎给予抗生素降阶梯治疗可以控制感染病症,提升抗生素科学使用水平,缩短患儿治疗时长,疗效显著,可推广应用。

Objective To analyze and investigate the clinical effect of antibiotic step-down therapy treating severe pneumonia in children. Methods 80 children with severe pneumonia admitted into our hospital in recent years were selected as the research objects,and according to the digital ballot method,they were randomly divided into the study group and the control group,there were 40 cases in each group.The study group was treated with antibiotic step-down therapy,while the control group was treated with routine antibiotic,the treatment effect of the two groups were compared. Results The cure rate was 40.0% and the total effective rate was 85.0% in the study group,while the cure rate was 15.0%,and the total effective rate was 70.0% in the control group,the treatment effect of the study group was better than that in the control group （P〈0.05）.The control time for infected disease and hospital stay in the study group were significantly shorter than those in the control group （P〈0.05）.Two groups of children during treatment did not appear serious adverse reactions. Conclusion For children with severe pneumonia,antibiotic step-down therapy can control infection symptoms,and improve the scientific using level,and can shorten the treatment time,and its effect is obvious.It may be promoted and applied.