红树白骨壤果实中生物碱类化学成分研究

Alkaloids from the Mangrove Avicennia marina

【目的】研究红树白骨壤果实中生物碱类化学成分。【方法】采用多种柱色谱和高效液相色谱分离技术,对白骨壤果实中生物碱类化学成分进行研究,运用波谱分析和文献对照方法,鉴定化学结构。【结果】白骨壤果实中分离鉴定了5个生物碱类单体化合物,分别鉴定为2(1H)-Pyrazinone-3,4-dihydro-1,3,5-trimethyl(1)、尿苷(2)、尿嘧啶(3)、indole-3-aldehyde(4)、Miazole(5)。【结论】化合物1,4-5均是首次从该种海洋植物中分离得到。

[Objective]To investigate the marine alkaloids form mangrove Avicennia marina. [Methods]The marine alkaloids were isolated and purified by column chromatography on silica gel and their structures were identified by spectral analyses and comparison with literatures. [Results]Five compounds were obtained from A. marina and characterized as 2 （ 1 H）- Pyrazinone, 3,4-dihydro-1,3,5-trimethyl（ 1 ） , Uridine （ 2 ）, Uracil （ 3 ） , indole-3-aldehyde （ 4 ）, Miazole （5）. [Conclusion]Compounds 1 and 4-5 were isolated from Avicennia marina for the first time.