国内免疫接种领域系统评价/Meta分析的质量评价

Quality assessment for Chinese systematic reviews /Meta-analysis on immunization

目的:对国内发表的免疫接种领域系统评价/Meta分析的方法学和发表质量进行评价。方法:计算机检索CNKI、WANFANG、VIP及CBM数据库,检索时间从建库至2013年11月,查找免疫接种领域的系统评价/Meta分析的中文文献,采用R-AMSTAR和PRISMA量表对文献的方法学质量和发表质量进行评价。结果:最终纳入32篇文献。文献方法学质量主要存在文献检索不全面、未提供排除文献清单和筛选流程图、缺乏纳入研究的科学性评价及运用,对研究间异质性处理不当,对发表偏倚控制不足等问题。报告质量的主要问题表现在摘要、纳入排除标准、资料搜集及提取方法、结果及讨论等方面报道不全面。结论:国内已发表的免疫接种领域系统评价/Meta分析的方法学质量及报告质量仍存在一定程度的问题,有待进一步提高和规范。

To assess the methodology and report quality of Chinese systematic reviews /Meta-analysis on immunization.Methods： All literatures of systematic reviews/Meta-analysis on immunization were searched in the four Chinese databases：CNKI,WANFANG Database,VIP and CBM from the establishment date to November 2013.Methodology quality and report quality of included reviews were evaluated by R-AMSTAR scale and PRISMA scale.Results：32 literatures were identified.The main problems of methodology quality were insufficient in a comprehensive literature search , lack of the list of excluded studies and the selection process ,lack of the documented assessment of the scientific quality of included studies and the appropriate use of the scientific quality in forming conclusions , inappropriate dealing with heterogeneity of data , insufficient in control of publication bias.The main problems of report quality were incomplete report in abstract , inclusion and exclusion criteria , data collection and analysis methods , result and discussion.Conclusion： The methodology quality and report quality of included literatures have more or less flaws in different levels.Further improvement of methodological quality and reporting is required in order to increase the quality of these studies .