职业暴露异氰酸酯生物标志物的研究进展

Research progress on diisocyanate biomarkers of occupational exposure

异氰酸酯是导致职业性哮喘的主要致病因素之一,选择合适的异氰酸酯生物标志物,对开展异氰酸酯暴露的生物监测,实现异氰酸酯易感者的早期预警、早期干预等具有重要的意义。作者就职业暴露异氰酸酯生物标志物的研究进展做一综述,以期为更好地保护异氰酸酯暴露者提供依据。

Diisocyanates are confirmed as the main risk factor for occupational asthma. It is essential to choose the appropriate biomarkers of diisocyanate, to carry out the biological monitoring of diisocyanate exposure, and realize the early warning and early intervention among workers who are susceptible to diisocyanate. The authors review the research progress on diisocyanate biomarkers of occupational exposure, in order to provide the basis for protecting the workers exposed to diisocyanate.